Date/Time
Date(s) - Fri 27 June
12:00
Location
Seminar Room, Malaghan Institute, VUW
Malaghan Institute seminar
Metabolic Control of Influenza Virus Infection
Influenza remains a global health threat, especially for high-risk populations. Beyond classical antiviral and vaccine-based strategies, host metabolic pathways offer a promising alternative. In this talk, Mustapha Si-Tahar will present recent findings from his lab on the immunomodulatory and antiviral properties of endogenous metabolites. These molecules not only reduce inflammation but also impair viral replication, offering dual therapeutic potential. Our data open new perspectives for the development of host-directed therapies against influenza virus infection.
Bio:
Mustapha Si-Tahar is the Director of the Research Center for Respiratory Diseases (CEPR), located in Tours, France. He oversees the center’s activities, which encompass 4 INSERM research teams and approximately 90 staff members, and also serves as deputy-leader of the “Pathophysiology of Lung Infections” team. He earned his Ph.D. in vascular inflammation from the Pasteur Institute in Paris in 1997, then completed postdoctoral training in mucosal innate immunity at Emory University (Atlanta) and Massachusetts General Hospital (Boston).
Dr. Si-Tahar joined the French National Institute of Health (INSERM) in 2001 and continued his research at the Pasteur Institute, focusing on key sensors and signaling pathways involved in lung epithelial responses to bacterial and viral infections. In 2012, he relocated to Tours city to establish the CEPR. He has extensive expertise in lung epithelial-driven innate immune responses to influenza virus.
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